What is Myasthenia Gravis?

Myasthenia Gravis (MG) is a chronic autoimmune neuromuscular disorder characterized by weakness and fatigue of voluntary muscles, especially those involved in movement and control. In MG, the body's immune system produces antibodies that block or impair the transmission of nerve impulses to the muscles, leading to muscle weakness and fatigue that worsen with activity and improve with rest. Myasthenia Gravis can affect people of any age but is most commonly diagnosed in women under 40 and men over 60.

Common Symptoms of Myasthenia Gravis​

Muscle Weakness

Weakness and fatigue, especially in muscles involved in facial expressions, chewing, swallowing, speaking, and eye movements (ocular muscles).

Ptosis

Drooping of the eyelids (ptosis) that may worsen throughout the day or with prolonged use of the affected muscles.

Diplopia

Double vision (diplopia) caused by weakness or paralysis of the muscles that control eye movement, resulting in misalignment of the eyes.

Dysphagia

Difficulty swallowing (dysphagia) or choking, especially with solid foods or liquids.

Fatigue

Generalized fatigue or weakness that worsens with physical activity and improves with rest.

Muscle Atrophy

Loss of muscle mass (atrophy) in severe or long-standing cases of Myasthenia Gravis.

Whom to Consult?​ and When to Consult?​

If you experience symptoms suggestive of Myasthenia Gravis or have concerns about muscle weakness or fatigue, it’s essential to seek medical evaluation and appropriate management at SRM Global Hospitals, Chennai.

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Common FAQs About Myasthenia Gravis

Q: What causes Myasthenia Gravis?

A: Myasthenia Gravis is an autoimmune disorder in which the body's immune system produces antibodies that target and attack neuromuscular junctions, impairing nerve-muscle communication. The exact cause of this autoimmune response is not fully understood but may involve genetic, environmental, and immunological factors.

Q: How is Myasthenia Gravis diagnosed?

A: Diagnosis of Myasthenia Gravis typically involves a medical history, physical examination, neurological assessment, specialized tests such as electromyography (EMG), nerve conduction studies, blood tests to detect specific antibodies (such as acetylcholine receptor antibodies), and imaging studies to evaluate muscle function.

Q: What is the treatment for Myasthenia Gravis?

A: Treatment for Myasthenia Gravis aims to improve muscle strength, reduce symptoms, and prevent complications. It may include medications (such as acetylcholinesterase inhibitors, immunosuppressants, or corticosteroids), thymectomy (surgical removal of the thymus gland), plasmapheresis (removal of antibodies from the blood), intravenous immunoglobulin (IVIG) therapy, or supportive interventions to manage symptoms and improve quality of life.

Q: Can Myasthenia Gravis be cured?

A: While there is no cure for Myasthenia Gravis, treatment options are available to manage symptoms and improve quality of life for individuals with the condition. With appropriate management, many people with Myasthenia Gravis lead fulfilling lives and experience periods of remission or symptom improvement.